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Glycoconjugate binding of gastric and enterohepatic Helicobacter spp. (2003)

Glycoconjugate binding of gastric and enterohepatic Helicobacter spp. (2003)

Hynes S O , Roche N , Teneberg S , Wadstrom T

Infection and Immunity, 2003; vol. 71 no. 5: 2976-2980

PubMed Id : 12704182

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- Gangliotetraosylceramide (Asialo-GM1, GgO4, Gg4, GA1, Asialo-GM1a)
- Lactosylceramide (CDH, LacCer, Lc2)
- Lactotetraosylceramide (Lc4)
- Isoglobotriaosylceramide (Isoglobotri, IGb3)
- Lewis b (Leb-6)

Glycan Structure Format

SNFG Traditional Oxford

Ligands

Ligand (5)

Ligand

Gangliotetraosylceramide (Asialo-GM1, GgO4, Gg4, GA1, Asialo-GM1a)
Lactosylceramide (CDH, LacCer, Lc2)
Isoglobotriaosylceramide (Isoglobotri, IGb3)
Lactotetraosylceramide (Lc4)
Lewis b (Leb-6)

Biological Associations

Agent (8) Lectin (33) Affected area (1)

Agent

H. bilis CCUG 38995
H. canis CCUG 33835
H. felis CCUG 28539
H. hepaticus CCUG 33637
H. mustelae 23950/1
H. mustelae 25715
H. pylori CCUG 17874
H. pylori CCUG 17875

Lectin

N/S (H. pylori CCUG 17874)
N/S (H. pylori CCUG 17874)
N/S (H. pylori CCUG 17874)
N/S (H. pylori CCUG 17875)
N/S (H. pylori CCUG 17875)
N/S (H. pylori CCUG 17875)
N/S (H. pylori CCUG 17875)
N/S (H. pylori CCUG 17875)
N/S (H. bilis CCUG 38995)
N/S (H. bilis CCUG 38995)
N/S (H. bilis CCUG 38995)
N/S (H. bilis CCUG 38995)
N/S (H. canis CCUG 33835)
N/S (H. canis CCUG 33835)
N/S (H. canis CCUG 33835)
N/S (H. canis CCUG 33835)
N/S (H. felis CCUG 28539)
N/S (H. felis CCUG 28539)
N/S (H. felis CCUG 28539)
N/S (H. felis CCUG 28539)
N/S (H. hepaticus CCUG 33637)
N/S (H. hepaticus CCUG 33637)
N/S (H. hepaticus CCUG 33637)
N/S (H. hepaticus CCUG 33637)
N/S (H. mustelae 23950/1)
N/S (H. mustelae 23950/1)
N/S (H. mustelae 23950/1)
N/S (H. mustelae 23950/1)
N/S (H. mustelae 25715)
N/S (H. mustelae 25715)
N/S (H. mustelae 25715)
N/S (H. mustelae 25715)
N/S (H. pylori CCUG 17874)

Affected Area

Stomach (Human)

Diseases

Disease (3)

Disease

Chronic gastritis
Peptic ulcers
Gastric cancer

Experimental methods

Bacteria tested in HA assay

HA inhibition assay

Autoradiogram applied to thin-layer chromatography (TLC)

Chemical detection of glycosphingolipid and chromatogram assay detection of their binding

Sources

Biological : Unknown / organism : null / supplier : Sigma Chemical Co

Biological : Cat intestine

Biological : Human meconium

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