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SugarBind

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Agent Structures

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SugarBind >
Lectins >
SabA

SabA

Agent : Helicobacter pylori CCUG 17874

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- G9-B
- Sialyl Lewis x Lewis x (NeuAca3-dimer-Lex, SDLex)
- Sialyl Lewis x (SLex, NeuAca3-Lex)
- VIM-2
- Sialosylparagloboside (S3P, NeuAca3SPG, IV3(NeuAc)nLc4Cer, Sial pg, NeuAca2-3PG, S-3-PG)
- I-active ganglioside (NeuAca3-nLc6, NeuAca2-3i)
- NeuAca3-nLc8
- I-Active ganglioside (NeuAc-G-10, NeuAca2-3I)

References

Title	Year	Authors	Pubmed
Helicobacter pylori and complex gangliosides	2004	Roche et al.	14977958

3D structure from PDB

No PDB available

Glycan Structure Format

SNFG Traditional Oxford

Gene

-

Uniprot

Supporting structure

Fimbria : Unnamed

Ligands

Ligand (8)

Ligand

G9-B
Sialyl Lewis x Lewis x (NeuAca3-dimer-Lex, SDLex)
Sialyl Lewis x (SLex, NeuAca3-Lex)
VIM-2
Sialosylparagloboside (S3P, NeuAca3SPG, IV3(NeuAc)nLc4Cer, Sial pg, NeuAca2-3PG, S-3-PG)
I-active ganglioside (NeuAca3-nLc6, NeuAca2-3i)
NeuAca3-nLc8
I-Active ganglioside (NeuAc-G-10, NeuAca2-3I)

Biological Associations

Agent (1) Lectin (1) Affected area (1)

Agent

H. pylori CCUG 17874

Lectin

SabA (H. pylori CCUG 17874)

Affected Area

Stomach (Human)

Glyco3D (CERMAV)

-

CFG

-

Diseases

Disease (3)

Disease

Chronic gastritis
Peptic ulcers
Gastric cancer

Experimental methods

GL isolated and characterized by FAB and EI MS and proton NMR

Binding investigated by using thin-layer chromatography (TLC)

SugarBind

Supported by Swiss National Science Foundation (SNSF) | SIB