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Gp120

Agent : Lentivirus Human Immunodeficiency Virus Type 1

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References

Title Year Authors Pubmed
Binding of human immunodeficiency virus type 1 (HIV-1) gp120 to galatosylceramide (GalCer): relationship to the V3 loop. 1994 Cook et al. 8184533
Infection of colonic epithelial cell lines by type 1 human immunodeficiency virus is associated with cell surface expression of galactosylceramide, a potential alternative gp120 receptor 1993 Fantini et al. 8464878

3D structure from PDB

No PDB available

Glycan Structure Format

SNFG Traditional Oxford

Gene

env

Uniprot

P18799

Supporting structure

Unknown : N/S

Ligands

Biological Associations

Glyco3D (CERMAV)

-

CFG

-

Diseases

Experimental methods

High performance thin layer chromatography (HPthin-layer chromatography (TLC)) binding assay

Monoclonal antibody (MAb) blocking of Gp120-GalCer binding

Binding of MAbs to sulfatide-bound Gp120

ELISA, removal of N-linked oligosaccharides

Inhibition of infection by anti-GalCer monoclonal anti-bodies

Immunofluorescence labeling

Glycolipid analysis

Gp120 binding

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Supported by Swiss National Science Foundation (SNSF)  |  SIB