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Carbohydrate binding specificity of the neutrophil-activating protein of Helicobacter pylori (1997)

Carbohydrate binding specificity of the neutrophil-activating protein of Helicobacter pylori (1997)

Evans D G , Lampert H C

Journal of Biological Chemistry, 1997 Jul 25; vol. 272 no. 30: 19067-19071

PubMed Id : 9228091

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- Sulfatide
- Sulf-gangliotetraosyl ceramide
- Gangliotetraosylceramide (Asialo-GM1, GgO4, Gg4, GA1, Asialo-GM1a)
- I-active ganglioside (NeuAca3-nLc6, NeuAca2-3i)
- NeuAca3-nLc8
- Fuc-gangliotetraosylceramide (H-5-ganglio, Fuc-GgO4)
- Unnamed
- Unnamed
- Neolactotetraosylceramide (NLc4, Paragloboside)

Glycan Structure Format

SNFG Traditional Oxford

Ligands

Ligand (9)

Ligand

Fuc-gangliotetraosylceramide (H-5-ganglio, Fuc-GgO4)
Gangliotetraosylceramide (Asialo-GM1, GgO4, Gg4, GA1, Asialo-GM1a)
Unnamed
Unnamed
Sulfatide
Sulf-gangliotetraosyl ceramide
I-active ganglioside (NeuAca3-nLc6, NeuAca2-3i)
NeuAca3-nLc8
Neolactotetraosylceramide (NLc4, Paragloboside)

Biological Associations

Agent (1) Lectin (9) Affected area (1)

Agent

H. pylori N/S

Lectin

N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)
N/S (H. pylori N/S)

Affected Area

Stomach (Human)

Diseases

Disease (3)

Disease

Chronic gastritis
Peptic ulcers
Gastric cancer

Experimental methods

Thin-layer chromatography (TLC)

Microtiter well assay

Hemagglutination assay

Sources

Biological : Unknown / organism : null / supplier : Sigma Chemical Co

Biological : Chemically treated erythrocyte / organism : Human

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