Ligand Search
Search the ligands by systematic name, abbreviated name, synonyms or IUPAC encoding
SNFG, Text, Oxford| Ligand Names | Glycoconjugate Type | Ligand Types | Glycan | Cartoon |
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| Unnamed | - | NeuGc(a2-3)Gal(b1-4)GlcNAc |
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| - | NeuAc(a2-3)(2F)Gal(b1-4)GlcNAc | No cartoon for structure 174 | ||
| - | NeuAc(a2-3)(2F)Gal(b1-3)GlcNAc | No cartoon for structure 173 | ||
| - | NeuAc(a2-3)Gal(b1-4)GlcNAc |
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| - | NeuAc(a2-3)Gal(b1-4)GlcNAc(b |
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| - | NeuAc(a2-3)Gal(b1-3)GlcNAc |
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| - | NeuAc(a2-3)Gal(b1-3)[HSO3(-6)]GlcNAc(b |
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| - | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)][HSO3(-6)]GlcNAc(b |
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| - | NeuAc(a2-6)Gal(b1-4)GlcNAc |
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| - | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc |
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| - | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal |
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| Glycosphingolipid | - | Gal(a1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc |
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| - | Fuc(a1-2)Gal(b1-3)GlcNAc |
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| - | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc |
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| - | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal |
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| - | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc |
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| Glycoprotein | GlcNAc(b1-4)GlcNAc |
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| Glycosphingolipid | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-8)NeuAc(2-3) |
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| Glycosphingolipid | Fuc(a1-2)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| - | Fuc |
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| Glycosphingolipid | - | Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| - | Gal(a1-4)Gal |
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| Glycosphingolipid | Gal(a1-4)Gal(b1-1) |
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| Glycosphingolipid | - | Gal(a1-4)Gal(b1-1) |
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| - | Gal |
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| - | Gal(b |
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| - | Gal(b1 |
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| Glycosphingolipid | - | Gal(b1-1) |
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| Glycosphingolipid | - | Gal(b1-4)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(b1-3)GalNAc(b1-4)[SU-3]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| - | - | Gal(b1-3)GlcNAc |
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| Glycosphingolipid | - | Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| - | Glc |
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| Glycosphingolipid | - | Glc(b1-1) |
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| - | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(b1-3)GalNAc(b1-4)[NeuGc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | Gal(a1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc |
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| Glycosphingolipid | - | Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | Gal(a1-4)Glc(b1-1) |
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| - | - | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc |
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| Glycosphingolipid | - | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycoprotein | Gal(b1-3)GalNAc |
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| Glycoprotein | NeuAc(a2-3) |
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| Glycoprotein | Gal(b1-3)GalNAc |
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| Glycoprotein | NeuAc(a2-3) |
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| - | Gal(b1-3)[Fuc(a1-4)]GlcNAc |
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| Glycosphingolipid | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc |
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| Glycosphingolipid | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | Gal(b1-4)[Fuc(a1-3)]GlcNAc |
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| Glycosphingolipid | Gal(b1-3)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | Fuc(a1-2)Gal(b1-4)[Fuc(a1-3)]GlcNAc |
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| - | - | Man(a) |
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| - | Man |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| - | GalNAc(b |
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| - | GalNAc |
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| Glycoprotein | GlcNAc |
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| - | NeuAc(a2-3) |
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| Glycoprotein | NeuAc(a2-8) |
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| - | NeuAc |
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| Glycosphingolipid | - | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | - | Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc |
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| N-linked glycoprotein | - | Man(a1-3)[Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc |
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| - | Gal(b1-3)GlcNAc(b1-3)Gal |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-3)GlcNAc(b |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-4)Glc |
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| - | NeuAc(a2-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)[Fuc(a1-3][HSO3(-6)]GlcNAc(b1-3)[HSO3(-6)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(b1-4)[NeuAc(a2-6)]GlcNAc(b1-3)Gal(b1-4)Glc |
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| Glycosphingolipid | NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-4)[HSO3(-6)]GlcNAc(b |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| N-linked glycoprotein | - | Man(a1-3)Man |
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| N-linked glycoprotein | - | Man(a1-6)Man |
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| N-linked glycoprotein | Man(a1-2)Man |
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| Glycosphingolipid | GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(a1-3)[Fuc(a1-2)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc |
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| Unnamed | - | NeuAc(a2-6)Gal |
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| Glycosphingolipid | SO4(-3)Gal(b1-1) |
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| Glycosphingolipid | SO4(-3)Gal(b1-4)Glc(b1-1) |
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| - | Gal(a1-6)Gal |
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| Unnamed | - | Gal(a1-4)Gal(b1-4)Glc(b |
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| Unnamed | - | - | Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc |
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| Unnamed | - | Gal(a1-4)Gal(b1-1)Glc |
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| Unnamed | O-linked glycoprotein | NeuAc(a2-3)Gal(b1-3)[NeuAc(a2-6)]GalNAc |
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| Glycosphingolipid | Gal(b1-3)Gal(b1-4)GlcNAc(b1-6)[NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | Gal(b1-3)GalNAc |
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| Unnamed | Glycosphingolipid | - | GalNAc(b1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1) |
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| Unnamed | Glycosphingolipid | - | GalNAc(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | GalNAc(b1-4)Gal |
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| Unnamed | Glycosphingolipid | - | GalNAc(b1-3)[Gal(a1-3)]Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuGc(a2-3)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | Gal(b1-4)GlcNAc |
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| Unnamed | Glycosphingolipid | - | Gal(a1-4)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-8)NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | NeuAc(a2-3)Gal(b1-3)GalNAc |
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| Glycosphingolipid | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| - | Gal(a1-3)[Fuc(a1-2)]Gal |
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| Unnamed | Glycosphingolipid | - | Gal(a1-3)Gal(a1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GalNAc(a1-3)GalNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GalNAc(a1-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Fuc(a1-2)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | NeuGc(a2-3)Gal(b1-4)Glc |
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| Glycosphingolipid | Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-6)[Gal(b1-3)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | - | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4) |
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| - | Gal(b |
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| Glycosphingolipid | - | Gal(b1-4)GlcNAc(b1-6)[Gal(b1-3)]GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | NeuAc(a2-3)Gal(b1-4)GalNAc |
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| Glycosphingolipid | NeuAc(a2-8)NeuAc(a2-3)Gal(b1-4)Glc(b1-1) |
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| N-linked glycoprotein | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc |
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| Glycosphingolipid | Gal(a1-3)[Fuc(a1-2)]Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycoprotein | Man(a1-3)[Man(a1-6)]Man(a1-6)[Man(a1-2)Man(a1-3)]Man |
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| Glycosphingolipid | SO3Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | Glycoprotein | Fuc(a1-2)Gal(b1-3)[Fuc(a1-4)]Gal |
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| Glycosphingolipid | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(a1-3)Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-3)Gal(b1-4)Glc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | - | Man(a1-2)Man |
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| Unnamed | - | GalNAc(b1-4)Gal(b1-4)Glc |
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| Glycosphingolipid | SO4(-6)Gal(b1-1) |
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| - | GalNAc(a1-3)[Fuc(a1-2)]Gal |
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| - | - | Man(a1-3)[Man(1-6)]Man |
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| - | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal |
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| Glycosphingolipid | SO3Gal(b1-1) |
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| Glycosphingolipid | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Gal(b1-4)GlcNAc(b1-6)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-3)]Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | Gal(b1-3) |
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| Unnamed | - | Gal(b1-4) |
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| Unnamed | - | - | Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc |
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| Unnamed | - | - | GlcNAc(b1-3)Gal |
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| Unnamed | - | Gal(a1-4)Gal(b1-4)GlcNAc |
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| Unnamed | - | Gal(a1-4)Gal(b1-4)Glc |
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| N-linked glycoprotein | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-4)[NeuAc(a2-6)Gal(b1-4)GlcNAc(b1-2)]Man(a1-3)[NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)GlcNAc |
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| - | Gal(b1-4)GlcNAc(b1-2)Man(a1-3)[Gal(b1-4)GlcNAc(b1-2)Man(a1-6)]Man(b1-4)GlcNAc(b1-4)[Fuc(a1-6)]GlcNAc |
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| Glycosphingolipid | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| - | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | Glycosphingolipid | Gal(b1-3)[NeuAc(a2-6)]GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | Gal(b1-3)GlcNAc |
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| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | Gal(a1-4)Gal(b |
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| Glycosphingolipid | - | GalNAc(a1-3)GalNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | SO3(-3)Gal(b1-1) |
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| Unnamed | Glycoprotein | Fuc(a1-2)Gal(b1-4)GlcNAc |
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| Glycosphingolipid | NeuAc(a2-3)Gal(b1-3)GalNAc(b1-4)Gal(b1-4)Glc(b1-1) |
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| Unnamed | - | NeuAc(a2-3)Gal(b1-4) |
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| Unnamed | - | GlcNAc(b1-3)Gal(b1-4)Glc |
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| - | Fuc(a1-2)Gal |
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| Unnamed | O-linked glycoprotein | GalNAc(b1-4)[NeuGc(a2-3)]Gal(B |
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| - | - | Man(a1-2)Man(a1-6)Man(a1-6) |
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| Unnamed | - | Gal(b1-4)Glc |
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| Glycosphingolipid | GalNAc(b1-4)[NeuAc(a2-3)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | NeuGc(a2-3)[GalNAc(b1-4)]Gal(b1-4)Glc(b1-1) |
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| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)GlcNAc(b1-3)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
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| Glycoprotein | Man(a1-3)[Man(a1-6)]Man(a1-6)Man(a1-3)Man |
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| Glycoprotein | - | Man(a1-3)Man(a1-4)GlcNAc |
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| Unnamed | - | - | Man(high) |
|
| - | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc |
|
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| - | Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc |
|
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| Glycosphingolipid | - | GalNAc(a1-3)GalNAc(b1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
|
|
| Unnamed | - | Gal(b1-3)GalNAc(b1-4)[NeuAc(a2-3)]Gal |
|
|
| Unnamed | Glycosphingolipid | - | Gal(a1-3)Gal(a1-4)Gal(b1-4)Glc(b1-1) |
|
| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)[Fuc(a1-3)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
|
||
| Glycosphingolipid | NeuAc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
|
||
| Unnamed | Glycoprotein | NeuAc(a2-3)[Gal(b1-4)]GlcNAc(b1-3)Gal(b1-4)GlcNAc |
|
|
| - | NeuAc(a2-6)Gal(b1-3)GlcNAc(b1-3)Gal(b1-4)Glc |
|
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| Glyceroglycolipid | SO4(-3)Gal(b1-3) |
|
||
| Unnamed | - | GalNAc(b1-3)Gal |
|
|
| - | NeuAc(a2-3)Gal |
|
||
| Unnamed | - | Gal(a1-3)Gal(b1-4)GlcNAc(b |
|
|
| Unnamed | Glycosphingolipid | NeuGc(a2-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
|
|
| Unnamed | - | - | Gal(b1-4)GalNAc |
|
| Glycosphingolipid | Gal(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
|
||
| Glycosphingolipid | GalNAc(a1-3)[Fuc(a1-2)]Gal(b1-3)[Fuc(a1-4)]GlcNAc(b1-3)Gal(b1-4)Glc(b1-1) |
|
||
| - | NeuAc(a2-3)Gal(b |
|
||
| - | - | Man(a1-3)Man(a1-6)Man |
|
|
| Unnamed | Glycoprotein | GlcNAc(b1-4)GlcNAc |
|
|
| Glycosphingolipid | SO3(-3)Gal(b1-4)Glc(b1-1) |
|
||
| Unnamed | - | Gal(a1-3)Gal |
|
SugarBind 
Supported by Swiss National Science Foundation (SNSF) | SIB