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Structure

Details for this glycan structure

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References

Title Year Authors Pubmed
Functional adaptation of BabA, the H. pylori ABO blood group antigen binding adhesin 2004 Aspholm-Hurtig et al. 15273394
Structural insight in histo-blood group binding by the F18 fimbrial adhesin FedF 2012 Moonens et al. 22812428
Norovirus and histo-blood group antigens: demostration of a wide spectrum of strain specificities and classification of two major binding groups among multiple binding patterns. 2005 Huang et al. 15890909

Glycan Structure Format

SNFG Traditional Oxford

IUPAC

Fuc(a1-2)Gal(b1-3)GlcNAc

GlycoCT

RES
1b:x-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(2+1)4d


Glycan references

Glytoucan : G88393MK

Substructure search

50 structures in GlyConnect contains this substructure

Ligands

Biological Associations

Diseases

Experimental methods

Back scattering interferometry (BSI)

X-ray crystallography

Microscale thermophoresis (MST)

Site-specific mutations in fedF introduced by overlap PCR

Surface plasmon resonance (SPR)

VLP binding to saliva-coated microtiter plates

MAbs specific to histo-blood group antigens

Inhibition of binding of FITC-labeled bacteria to gastric mucosa

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Supported by Swiss National Science Foundation (SNSF)  |  SIB