SugarBind

FedF

Agent : Escherichia coli N/S

View graph

References

Title Year Authors Pubmed
Structural insight in histo-blood group binding by the F18 fimbrial adhesin FedF 2012 Moonens et al. 22812428

3D structure from PDB

3D visualization by LiteMol

Glycan Structure Format

SNFG Traditional Oxford

Gene

fedF

Uniprot

Q47212

Supporting structure

Fimbria : F18

Ligands

    Ligand

  • Antigen H (H1 (tri-))
  • A6 type 1
  • H type 1
  • H5 type 1
  • B6 type 1

Biological Associations

    Affected Area

Glyco3D (CERMAV)

1591 (PDB : 4B4Q / Crystal Structure of the lectin domain of F18 fimbrial adhesin FedF in complex with blood group A type 1 hexasaccharide)

1592 (PDB : 4B4R / Crystal Structure of the lectin domain of F18 fimbrial adhesin FedF in complex with blood group B type 1 hexasaccharide)

CFG

Array : primscreen_PA_v2_178_11182005 (Protein : cbp_oth_other_369 )

Diseases

    Disease

Experimental methods

Back scattering interferometry (BSI)

X-ray crystallography

Microscale thermophoresis (MST)

Site-specific mutations in fedF introduced by overlap PCR

Surface plasmon resonance (SPR)

SugarBind Creative Commons License

Supported by Swiss National Science Foundation (SNSF)  |  SIB