SugarBind

Structure

Details for this glycan structure

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References

Title Year Authors Pubmed
Structural insight in histo-blood group binding by the F18 fimbrial adhesin FedF 2012 Moonens et al. 22812428
Noroviruses bind to human ABO, Lewis, amd secretor histo-group antigens: identification of 4 distinct strain-specific patterns 2003 Huang et al. 12825167

Glycan Structure Format

SNFG Traditional Oxford

IUPAC

Fuc(a1-2)Gal(b1-3)GlcNAc(b1-3)Gal

GlycoCT

RES
1b:x-dgal-HEX-1:5
2b:b-dglc-HEX-1:5
3s:n-acetyl
4b:b-dgal-HEX-1:5
5b:a-lgal-HEX-1:5|6:d
LIN
1:1o(3+1)2d
2:2d(2+1)3n
3:2o(3+1)4d
4:4o(2+1)5d


Glycan references

Glytoucan : G50899UD

Substructure search

32 structures in GlyConnect contains this substructure

Ligands

    Ligand

  • H type 1

Biological Associations

Diseases

Experimental methods

Back scattering interferometry (BSI)

X-ray crystallography

Microscale thermophoresis (MST)

Site-specific mutations in fedF introduced by overlap PCR

Surface plasmon resonance (SPR)

VLP binding to saliva-coated microtiter plates

MAbs specific to histo-blood group antigens

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Supported by Swiss National Science Foundation (SNSF)  |  SIB